Potent Antimalarial Activities of Polyether Antibiotic, X-206.

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Potent antimalarial activities of polyether antibiotic, X-206.

In the course of our screening program to discover antimalarial antibiotics, which are active against drug resistant Plasmodium falciparum in vitro and rodents infected with P. berghei in vivo, from the culture broth of microorganisms, we found a selective and potent active substance produced by an actinomycete strain K99-0413. It was identified as a known polyether antibiotic, X-206. We also c...

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ژورنال

عنوان ژورنال: The Journal of Antibiotics

سال: 2001

ISSN: 0021-8820,1881-1469

DOI: 10.7164/antibiotics.54.658